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Reynolds CF, Frank E, Dew MA, Houck PR, Miller M, Mazumdar S, et al

Alteration of tryptophan metabolism has been linked with inflammatory and immune responses, with tryptophan catabolism being recognized as an important player in inflammation and immune response [65, 66]

Amy Rothberg, a University of Michigan endocrinologist who directs a weight-management and diabetes treatment program

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Network-based drug repurposing has leveraged betweenness and closeness centrality to rank pathway significance and predict drug-disease associations 33,34 , while centrality metrics have also been used to examine disease co-occurrence and mechanistic overlaps 19,35